Cell

ERα is an RNA-binding protein sustaining tumor cell survival and drug resistance.

Cell

Xu Y, Huangyang P, Wang Y, Xue L, Devericks E, Nguyen HG, Yu X, Oses-Prieto JA, Burlingame AL, Miglani S, Goodarzi H, Ruggero D

Differential Requirements for eIF4E Dose in Normal Development and Cancer.

Cell

Truitt ML, Conn CS, Shi Z, Pang X, Tokuyasu T, Coady AM, Seo Y, Barna M, Ruggero D

Protein and Nucleotide Biosynthesis Are Coupled by a Single Rate-Limiting Enzyme, PRPS2, to Drive Cancer.

Cell

John T. Cunningham, Melissa V. Moreno, Alessia Lodi, Sabrina M. Ronen, Davide Ruggero